Publications

For the most up-to-date publications list,
please see Prof. Rege’s Google Scholar Page.

2020

• Ridha I., Gorenca P., Urie R., Shanbhag S.,(*) and Rege K. (*)
  Repulsion of Polar Gels From Water: Hydration‐Triggered Actuation, Self‐Folding, and 3D Fabrication.
  Adv. Mater. Interf. 2020:2000509.
• Ghosh D., Godeshala S., Nitiyanandan R., Islam MS., Yaron JR., DiCaudo D., Kilbourne J., and Rege K. (*)
  Copper-Eluting Fibers for Enhanced Tissue Sealing and Repair.
  ACS Appl. Mater. Interfaces 2020.
• Kim H., Tse Y., Webb A., Mudd E., Abedin MR., Mormile M., Dutta S., Rege K., and Barua S. (*)
  PolyRad–Protection Against Free Radical Damage.
  Sci Rep 2020, 20;10(1):1-3.
• Mangal JL., Inamdar S., Yang Y., Dutta S., Wankhede M., Shi X., Gu H., Green MD., Rege K., Curtis M., and Acharya A. (*)
  Metabolite Releasing Polymers Control Dendritic Cell Function by Modulating their Energy Metabolism.
  J. Mater. Chem. B. 2020.
• Subramaniam KP., Inamdar S., Dutta S., Bista T., Sokolowski T., Sapareto S., and Rege K. (*)
  Plasmonic Gel Nanocomposites for Detection of High Energy Electrons.
  J. Mater. Chem. B. 2020.
• Nath S, Pigula M, Khan AP, Hanna W, Ruhi MK, Dehkordy FM, Pushpavanam K, Rege K, Moore K, Tsujita Y, Conrad C., Inci, F., Carmen, G. del M., Franco, W., Celli, J., Demirci U., Hasan, T., Huang. H-Chiao., and Rizvi, I. (*)
  Flow-induced Shear Stress Confers Resistance to Carboplatin in an Adherent Three-Dimensional Model for Ovarian Cancer: A Role for EGFR-Targeted Photoimmunotherapy Informed by Physical Stress.
  J. Clin. Med. 2020;9(4):924.

2019

• Pushpavanam K., Inamdar S., Dutta S., Bista T., Sokolowski T., Boshoven E., Sapareto S., and Rege K. (*)
  Determination of Topographical Radiation Dose Profiles using Gel Nanosensors.
  Sci. Adv. 2019; 1;5(11):eaaw8704.
• Goklany S. (*), Lu P., Godeshala S., Hall A., Garrett-Mayer E., Voelkel-Johnson C., and Rege K. (*)
  Delivery of TRAIL-expressing Plasmid DNA to Cancer Cells in vitro and in vivo using Aminoglycoside-derived Polymers.
  J. Mater. Chem. B. 2019;7(44):7014-25.
• Thaker A., Pushpavanam K., Bista .T, Sapareto S., Rege K., and Nannenga BL. (*)
  Protein‐Facilitated Gold Nanoparticle Formation as Indicators of Ionizing Radiation.
  Biotechnol and Bioeng. 2019;116(12):3160-7.
• Zhang L., (*) Yaron JR., Tafoya AM., Wallace SE., Kilbourne J., Haydel S., Rege K., McFadden G., and Lucas AR. (*)
  A Virus-Derived Immune Modulating Serpin Accelerates Wound Closure with Improved Collagen Remodeling.
  J. Clin. Med. 2019;8(10):1626.
• Ghosh D., Urie R., Chang A., Nitiyanandan R., Lee JK., Kilbourne J., Rege K. (*)
  Light‐Activated Tissue‐Integrating Sutures as Surgical Nanodevices.
  Adv. Healthc. Mater. 2019;8(14):1900084.

2018

• Zhen Z., Potta T., Christensen MD., Narayanan E., Kanagal K., Breneman CM .,(*) and Rege K. (*)
  Accelerated Materials Discovery Using Chemical Informatics Investigation of Polymer Physicochemical Properties and Transgene Expression Efficacy.
  ACS Biomater Sci Eng. 2018; 20;5(2):654-69.
• Lin KN., Grandhi TS., Goklany S., and Rege K. (*)
  Chemotherapeutic Drug‐Conjugated Microbeads Demonstrate Preferential Binding to Methylated Plasmid DNA.
  Biotechnol J. 2018;13(11):1700701.
• Akar B., Pushpavanam K., Narayanan E., Rege K., and Heys JJ. (*)
  Mechanistic Investigation of Radiolysis-Induced Gold Nanoparticle Formation for Radiation Dose Prediction.
  Biomed Phys Eng Express. 2018; 9;4(6):065011.
• Urie R., Guo C., Ghosh D., Thelakkaden M., Wong V., Lee JK., Kilbourne J., Yarger J., and Rege K. (*)
  Rapid Soft Tissue Approximation and Repair Using Laser‐Activated Silk Nanosealants.
  Adv. Funct. Mater. 2018; 28(42):1802874.
• Gandhi NS., Godeshala S., Koomoa-Lange DL., Miryala B., Rege K., and Chougule MB. (*)
  Bioreducible Poly (amino ethers) based mTOR siRNA Delivery for Lung Cancer.
  Pharm. Res. 2018; 1;35(10):188.
• Christensen, M. D., Nitiyanandan, R., Meraji, S., Daer, R., Godeshala, S., Goklany, S., … & Rege, K. (2018). An inhibitor screen identifies histone-modifying enzymes as mediators of polymer-mediated transgene expression from plasmid DNA. Journal of controlled release.
• Candiello, J., Grandhi, T.S.P., Goh, S.K., Vaidya, V., Lemmon-Kishi, M., Eliato, K.R., Ros, R., Kumta, P.N., Rege, K. and Banerjee, I., (2018). 3D heterogeneous islet organoid generation from human embryonic stem cells using a novel engineered hydrogel platform. Biomaterials.
• Dobos, A., Grandhi, T. S. P., Godeshala, S., Meldrum, D. R., & Rege, K. (2018). Parallel fabrication of macroporous scaffolds. Biotechnology and bioengineering.
• Urie, R., Ghosh, D., Ridha, I., & Rege, K. (2018). Inorganic nanomaterials for soft tissue repair and regeneration. Annual review of biomedical engineering.
• Mushaben, M., Urie, R., Flake, T., Jaffe, M., Rege, K., & Heys, J. (2018). Spatiotemporal modeling of laser tissue soldering using photothermal nanocomposites. Lasers in surgery and medicine.
• Inamdar, S., Pushpavanam, K., Lentz, J. M., Bues, M., Anand, A., & Rege, K. (2018). Hydrogel Nanosensors for Colorimetric Detection and Dosimetry in Proton Beam Radiotherapy. ACS applied materials & interfaces.
• Elmer, J., Potta, T., & Rege, K. (2018). Synthesis of Cationic Polymer Libraries for Gene Delivery Using Diglycidyl Ethers. Targeted Drug Delivery.

2017

• Grandhi, T. S. P., Potta, T., Nitiyanandan, R., Deshpande, I., & Rege, K. (2017). Chemomechanically engineered 3D organotypic platforms of bladder cancer dormancy and reactivation. Biomaterials, 142, 171-185.
• Rege, K., & Mitragotri, S. (2017). Introduction to Special Issue: 2016 Translational Medicine and Bioengineering Conference. Bioengineering & translational medicine, 2(2), 137.
• Pushpavanam, K., Inamdar, S., Chang, J., Bista, T., Sapareto, S., & Rege, K. (2017). Detection of therapeutic levels of ionizing radiation using plasmonic nanosensor gels. Advanced Functional Materials, 27(21), 1606724.
• Pushpavanam, K., Chang, J., Sapareto, S., & Rege, K. (2017). Polypeptide-Facilitated Formation of Bimetallic Plasmonic Nanoparticles in Presence of Ionizing Radiation. Nano LIFE, 7(01), 1650006.
• Inamdar, S., Nitiyanandan, R., & Rege, K. (2017). Emerging applications of exosomes in cancer therapeutics and diagnostics. Bioengineering & translational medicine, 2(1), 70-80.
• Raravikar, N., Dobos, A., Narayanan, E., Grandhi, T. S. P., Mishra, S., Rege, K., & Goryll, M. (2017). Investigation into pseudo-capacitance behavior of glycoside-containing hydrogels. ACS applied materials & interfaces, 9(4), 3554-3561.
• Urie, R., Flake, T., & Rege, K. (2017). Laser Tissue Welding in Wound Healing and Surgical Repair. Bioengineering In Wound Healing: A Systems Approach (pp. 303-324).
• Zhen, Z., Potta, T., A Lanzillo, N., Rege, K., & M Breneman, C. (2017). Development of a Web-Enabled SVR-Based Machine Learning Platform and its Application on Modeling Transgene Expression Activity of Aminoglycoside-Derived Polycations. Combinatorial chemistry & high throughput screening, 20(1), 41-55.

2016

• Miryala, B., Godeshala, S., Grandhi, T. S. P., Christensen, M. D., Tian, Y., & Rege, K. (2016). Aminoglycoside-derived amphiphilic nanoparticles for molecular delivery. Colloids and Surfaces B: Biointerfaces, 146, 924-937.
• Ramos, J., & Rege, K. (2016). Comparative investigation of polymeric and nanoparticle vehicles for transgene delivery. Nano LIFE, 6(02), 1641001.
• Godeshala, S., Nitiyanandan, R., Thompson, B., Goklany, S., Nielsen, D. R., & Rege, K. (2016). Folate receptor‐targeted aminoglycoside‐derived polymers for transgene expression in cancer cells. Bioengineering & translational medicine, 1(2), 220-231.
• Elmer, J. J., Christensen, M. D., Barua, S., Lehrman, J., Haynes, K. A., & Rege, K. (2016). The histone deacetylase inhibitor Entinostat enhances polymer‐mediated transgene expression in cancer cell lines. Biotechnology and bioengineering, 113(6), 1345-1356.
• Pushpavanam, K., Narayanan, E., & Rege, K. (2016). Molecular and nanoscale sensors for detecting ionizing radiation in radiotherapy. ChemNanoMat, 2(5), 385-395.

2015

• Pushpavanam, K., Narayanan, E., Chang, J., Sapareto, S., & Rege, K. (2015). A colorimetric plasmonic nanosensor for dosimetry of therapeutic levels of ionizing radiation. ACS nano, 9(12), 11540-11550.
• Urie, R., Quraishi, S., Jaffe, M., & Rege, K. (2015). Gold nanorod-collagen nanocomposites as photothermal nanosolders for laser welding of ruptured porcine intestines. ACS Biomaterials Science & Engineering, 1(9), 805-815.
• Miryala, B., Feng, Y., Omer, A., Potta, T., & Rege, K. (2015). Quaternization enhances the transgene expression efficacy of aminoglycoside-derived polymers. International journal of pharmaceutics, 489(1-2), 18-29.
• Miryala, B., Zhen, Z., Potta, T., Breneman, C. M., & Rege, K. (2015). Parallel synthesis and quantitative structure–activity relationship (QSAR) modeling of aminoglycoside-derived lipopolymers for transgene expression. ACS Biomaterials Science & Engineering, 1(8), 656-668.
• Christensen, M. D., Elmer, J. J., Eaton, S., Gonzalez-Malerva, L., LaBaer, J., & Rege, K. (2015). Kinome-level screening identifies inhibition of polo-like kinase-1 (PLK1) as a target for enhancing non-viral transgene expression. Journal of controlled release, 204, 20-29.
• Urie, R., & Rege, K. (2015). Nanoscale inorganic scaffolds as therapeutics and delivery vehicles. Current Opinion in Chemical Engineering, 7, 120-128.

2014

• Pushpavanam, K., Santra, S., & Rege, K. (2014). Biotemplating plasmonic nanoparticles using intact microfluidic vasculature of leaves. Langmuir, 30(46), 14095-14103.
• Grandhi, T. S. P., Mallik, A., Lin, N., Miryala, B., Potta, T., Tian, Y., & Rege, K. (2014). Aminoglycoside antibiotic-derived anion-exchange microbeads for plasmid DNA binding and in situ DNA capture. ACS applied materials & interfaces, 6(21), 18577-18589.
• Ramos, J., Potta, T., Scheideler, O., & Rege, K. (2014). Parallel synthesis of poly (amino ether)-templated plasmonic nanoparticles for transgene delivery. ACS applied materials & interfaces, 6(17), 14861-14873.
• Grandhi, T., Potta, T., Faust, J., & Rege, K. (2014). Design of Bone Microenvironment Mimicking Antibiotic-based Hydrogels for Generation of Three Dimensional Tumor Models of Dormancy and Relapse.  2014 Society for Biomaterials Annual Meeting & Exposition.
• Gosnell, H., Kasman, L. M., Potta, T., Vu, L., Garrett-Mayer, E., Rege, K., & Voelkel-Johnson, C. (2014). Polymer-enhanced delivery increases adenoviral gene expression in an orthotopic model of bladder cancer. Journal of controlled release, 176, 35-43.
• Potta, T., Zhen, Z., Grandhi, T. S. P., Christensen, M. D., Ramos, J., Breneman, C. M., & Rege, K. (2014). Discovery of antibiotics-derived polymers for gene delivery using combinatorial synthesis and cheminformatics modeling. Biomaterials, 35(6), 1977-1988.
• Grandhi, T. S. P., & Rege, K. (2014). Design, synthesis, and functionalization of nanomaterials for therapeutic drug delivery. Nanomaterial (pp. 157-182).
• Grandhi, T. S. P., Potta, T., Taylor, D. J., Tian, Y., Johnson, R. H., Meldrum, D. R., & Rege, K. (2014). Sensitizing cancer cells to TRAIL-induced death by micellar delivery of mitoxantrone. Nanomedicine, 9(12), 1775-1788.

2013

• Elmer, J. J., Christensen, M. D., & Rege, K. (2013). Applying horizontal gene transfer phenomena to enhance non-viral gene therapy. Journal of controlled release, 172(1), 246-257.
• Ramos, J., & Rege, K. (2013). Poly (aminoether)–gold nanorod assemblies for shRNA plasmid-induced gene silencing. Molecular pharmaceutics, 10(11), 4107-4119.
• Walker, C. R., Pushpavanam, K., Nair, D. G., Potta, T., Sutiyoso, C., Kodibagkar, V. D., … & Rege, K. (2013). Generation of polypeptide-templated gold nanoparticles using ionizing radiation. Langmuir, 29(32), 10166-10173.
• Huang, H. C., Walker, C. R., Nanda, A., & Rege, K. (2013). Laser welding of ruptured intestinal tissue using plasmonic polypeptide nanocomposite solders. ACS nano, 7(4), 2988-2998.
• Ramos, J., Huang, H. C., & Rege, K. (2013). Laser targeting to nanoparticles for theranostic applications.  Handbook of Photomedicine (pp. 757-762).
• Ramos, J., Huang, H. C., & Rege, K. (2013). Delivery of Plasmid DNA to Mammalian Cells Using Polymer–Gold Nanorod Assemblies. Cellular and Subcellular Nanotechnology (pp. 81-91).

2012

• Labiano, A., Dai, M., Taylor, D., Young, W. S., Epps III, T. H., Rege, K., & Vogt, B. D. (2012). Slow release kinetics of mitoxantrone from ordered mesoporous carbon films. Microporous and Mesoporous Materials, 160, 143-150.
• Ramos, J., & Rege, K. (2012). Transgene delivery using poly (amino ether)‐gold nanorod assemblies. Biotechnology and bioengineering, 109(5), 1336-1346.
• Huang, H. C., Nanda, A., & Rege, K. (2012). Investigation of phase separation behavior and formation of plasmonic nanocomposites from polypeptide-gold nanorod nanoassemblies. Langmuir, 28(16), 6645-6655.
• Goryll, M., Lin, K. C., Wang, X., Ramakrishnan, S., Dey, S. K., Rege, K., & Ramakrishna, B. L. (2012). Biogenic Silica Nanopore Membranes on Micromachined Silicon Substrates. Biophysical Journal, 102(3), 204a.
• Borden, M., & Rege, K. (2012). Theranostic biocolloids: soft matter colloids for imaging and therapy. Theranostics, 2(12), 1115.
• Ramos, J., Taylor, D., & Rege, K. (2012). Gold nanoparticle mediated photo-chemotherapy. Journal of Nanomedicene and Nanotechnology, 3, 8-9.
• Vu, L., Ramos, J., Potta, T., & Rege, K. (2012). Generation of a focused poly (amino ether) library: polymer-mediated transgene delivery and gold-nanorod based theranostic systems. Theranostics, 2(12), 1160.

2011

• Sanyal, S., Huang, H., Rege, K., & Dai, L. L. (2011). Thermo-responsive core-shell composite nanoparticles synthesized via one-step pickering emulsion polymerization for controlled drug delivery. Journal of Nanomedicine & Nanotechnology, 2(7), 1-7.
• Taylor, D. J., Parsons, C. E., Han, H., Jayaraman, A., & Rege, K. (2011). Parallel screening of FDA-approved antineoplastic drugs for identifying sensitizers of TRAIL-induced apoptosis in cancer cells. BMC cancer, 11(1), 470.
• Barua, S., Ramos, J., Potta, T., Taylor, D., Huang, H. C., Montanez, G., & Rege, K. (2011). Discovery of cationic polymers for non-viral gene delivery using combinatorial approaches. Combinatorial chemistry & high throughput screening, 14(10), 908-924.
• Huang, H. C., Barua, S., Sharma, G., Dey, S. K., & Rege, K. (2011). Inorganic nanoparticles for cancer imaging and therapy. Journal of controlled Release, 155(3), 344-357.
• Huang, H. C., Yang, Y., Nanda, A., Koria, P., & Rege, K. (2011). Synergistic administration of photothermal therapy and chemotherapy to cancer cells using polypeptide-based degradable plasmonic matrices. Nanomedicine, 6(3), 459-473.

2010

• Chavez, V.L., Song, L., Barua, S., Li, X., Wu, Q., Zhao, D., Rege, K. and Vogt, B.D., (2010). Impact of nanopore morphology on cell viability on mesoporous polymer and carbon surfaces. Acta biomaterialia, 6(8), pp.3035-3043.
• Barua, S., & Rege, K. (2010). The influence of mediators of intracellular trafficking on transgene expression efficacy of polymer–plasmid DNA complexes. Biomaterials, 31(22), 5894-5902.
• Barua, S., Linton, R. S., Gamboa, J., Banerjee, I., Yarmush, M. L., & Rege, K. (2010). Lytic peptide-mediated sensitization of TRAIL-resistant prostate cancer cells to death receptor agonists. Cancer letters, 293(2), 240-253.
• Lin, K. C., Kunduru, V., Bothara, M., Rege, K., Prasad, S., & Ramakrishna, B. L. (2010). Biogenic nanoporous silica-based sensor for enhanced electrochemical detection of cardiovascular biomarkers proteins. Biosensors and Bioelectronics, 25(10), 2336-2342.
• Huang, H. C., Rege, K., & Heys, J. J. (2010). Spatiotemporal temperature distribution and cancer cell death in response to extracellular hyperthermia induced by gold nanorods. ACS nano, 4(5), 2892-2900.
• Rege, K., & Heng, M. (2010). Miniaturized parallel screens to identify chromatographic steps required for recombinant protein purification. nature protocols, 5(3), 408.
• HUANG, H. C., RAMOS, J., GRANDHI, T. S. P., POTTA, T., & REGE, K. (2010). Gold nanoparticles in cancer imaging and therapeutics. Nano Life, 1(03n04), 289-307.
• Ma, H., Luo, M., Sanyal, S., Rege, K., & Dai, L. (2010). The one-step Pickering emulsion polymerization route for synthesizing organic-inorganic nanocomposite particles. Materials, 3(2), 1186-1202.